[Cholesterol gallstone pathogenesis].

Title[Cholesterol gallstone pathogenesis].
Publication TypeJournal Article
Year of Publication1990
AuthorsMéndez N, Uribe M, Jessurun J, Uscanga L
JournalRev Invest Clin
Volume42 Suppl
Date Published1990 Jul
KeywordsAnimals, Bile, Bile Acids and Salts, Cholelithiasis, Cholesterol, Cholesterol, Dietary, Crystallization, Gallbladder, Gallstones, Humans, Hydrophobic and Hydrophilic Interactions, Mucins, Sciuridae, Solubility

Theoretically formation of cholesterol gallstone includes four steps, each one necessary for the next: 1) Metabolic or genetic defect, 2) Formation of supersaturated bilis, 3) Nucleation and 4) Growing of cholesterol crystals. In this work we review biliary physiology, each one of the mentionated steps and gallbladder alterations that have been to date investigated during lithogenesis.

Alternate JournalRev Invest Clin
PubMed ID19256135
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