Title | [Cholesterol gallstone pathogenesis]. |
Publication Type | Journal Article |
Year of Publication | 1990 |
Authors | Méndez N, Uribe M, Jessurun J, Uscanga L |
Journal | Rev Invest Clin |
Volume | 42 Suppl |
Pagination | 53-7 |
Date Published | 1990 Jul |
ISSN | 0034-8376 |
Keywords | Animals, Bile, Bile Acids and Salts, Cholelithiasis, Cholesterol, Cholesterol, Dietary, Crystallization, Gallbladder, Gallstones, Humans, Hydrophobic and Hydrophilic Interactions, Mucins, Sciuridae, Solubility |
Abstract | Theoretically formation of cholesterol gallstone includes four steps, each one necessary for the next: 1) Metabolic or genetic defect, 2) Formation of supersaturated bilis, 3) Nucleation and 4) Growing of cholesterol crystals. In this work we review biliary physiology, each one of the mentionated steps and gallbladder alterations that have been to date investigated during lithogenesis. |
Alternate Journal | Rev Invest Clin |
PubMed ID | 19256135 |
Related Faculty:
Jose Jessurun, M.D.