Title | The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms. |
Publication Type | Journal Article |
Year of Publication | 2022 |
Authors | Alaggio R, Amador C, Anagnostopoulos I, Attygalle AD, Araujo IBarreto de, Berti E, Bhagat G, Borges AMaria, Boyer D, Calaminici M, Chadburn A, Chan JKC, Cheuk W, Chng W-J, Choi JK, Chuang S-S, Coupland SE, Czader M, Dave SS, de Jong D, Du M-Q, Elenitoba-Johnson KS, Ferry J, Geyer J, Gratzinger D, Guitart J, Gujral S, Harris M, Harrison CJ, Hartmann S, Hochhaus A, Jansen PM, Karube K, Kempf W, Khoury J, Kimura H, Klapper W, Kovach AE, Kumar S, Lazar AJ, Lazzi S, Leoncini L, Leung N, Leventaki V, Li X-Q, Lim MS, Liu W-P, Louissaint A, Marcogliese A, L Medeiros J, Michal M, Miranda RN, Mitteldorf C, Montes-Moreno S, Morice W, Nardi V, Naresh KN, Natkunam Y, Ng S-B, Oschlies I, Ott G, Parrens M, Pulitzer M, S Rajkumar V, Rawstron AC, Rech K, Rosenwald A, Said J, Sarkozy C, Sayed S, Saygin C, Schuh A, Sewell W, Siebert R, Sohani AR, Tooze R, Traverse-Glehen A, Vega F, Vergier B, Wechalekar AD, Wood B, Xerri L, Xiao W |
Journal | Leukemia |
Volume | 36 |
Issue | 7 |
Pagination | 1720-1748 |
Date Published | 2022 Jul |
ISSN | 1476-5551 |
Keywords | Hematologic Neoplasms, Humans, Lymphoma, World Health Organization |
Abstract | We herein present an overview of the upcoming 5th edition of the World Health Organization Classification of Haematolymphoid Tumours focussing on lymphoid neoplasms. Myeloid and histiocytic neoplasms will be presented in a separate accompanying article. Besides listing the entities of the classification, we highlight and explain changes from the revised 4th edition. These include reorganization of entities by a hierarchical system as is adopted throughout the 5th edition of the WHO classification of tumours of all organ systems, modification of nomenclature for some entities, revision of diagnostic criteria or subtypes, deletion of certain entities, and introduction of new entities, as well as inclusion of tumour-like lesions, mesenchymal lesions specific to lymph node and spleen, and germline predisposition syndromes associated with the lymphoid neoplasms. |
DOI | 10.1038/s41375-022-01620-2 |
Alternate Journal | Leukemia |
PubMed ID | 35732829 |
PubMed Central ID | PMC9214472 |
Grant List | K08 CA267058 / CA / NCI NIH HHS / United States P30 CA008748 / CA / NCI NIH HHS / United States |
Related Faculty:
Amy Chadburn, M.D.