Title | Macrophage activation syndrome in a patient with axial spondyloarthritis on adalimumab. |
Publication Type | Journal Article |
Year of Publication | 2019 |
Authors | Baker R, Liew JW, Simonson PD, Soma LA, Starkebaum G |
Journal | Clin Rheumatol |
Volume | 38 |
Issue | 2 |
Pagination | 603-608 |
Date Published | 2019 Feb |
ISSN | 1434-9949 |
Keywords | Adalimumab, Adult, Cytokines, Humans, Macrophage Activation Syndrome, Macrophages, Male, Spondylarthritis, T-Lymphocytes |
Abstract | Macrophage activation syndrome (MAS) is a rare and potentially fatal condition characterized by excessive activation and uncontrolled proliferation of T lymphocytes and macrophages, leading to overwhelming systemic inflammation and cytokine release. MAS has been reported with viral infections, autoimmune disorders, malignancies, and medications. We describe a case of a patient with axial spondyloarthritis (axSpA) treated with adalimumab, who presented with MAS. |
DOI | 10.1007/s10067-018-4387-5 |
Alternate Journal | Clin Rheumatol |
PubMed ID | 30535729 |
PubMed Central ID | PMC7087649 |
Related Faculty:
Paul Simonson, M.D., Ph.D.