September 9, 2020
We are pleased to announce that several faculty (Drs. Borczuk, Mosquera, Imielinski and Ince) in the Department have received grants from the New York Genome Center, to address the role of ethnicity in several major cancer types.
The award-winning cancer research projects include:
“Ethnic-based Differences Between East Asian and Caucasian Patients in Genomic, Transcriptomic and Immune Profiles of Pre-invasive and Invasive Adenocarcinoma of the Lung,” a study that aims to identify the somatic alterations in non-solid lung nodules in East Asian and Caucasian patients that explain the significant demographic, clinical and biological differences between these two groups. The multi-disciplinary research team includes Drs. Nasser Altorki, Alain Borczuk, Timothy McGraw, Giuseppe Giacconi, Olivier Elemento, Weill Cornell Medicine.
“Molecular Links between Ancestry and Outcome Disparity in Breast and Prostate Cancer Patients Across the African Diaspora in New York City,” a study to identify molecular links between African ancestry and aggressive forms of breast and prostate cancer and investigate these as a source of racial disparities in cancer outcomes. Co-PIs include: Drs. Olivier Elemento, Cora Sternberg, Juan Miguel Mosquera, Melissa Davis, Weill Cornell Medicine; Dr. Marcin Imielinski, New York Genome Center; Dr. Paz Polak, Icahn School of Medicine at Mount Sinai; Dr. Lisa Newman, NewYork-Presbyterian Hospital.
“Mechanisms of Endometrial Cancer Disparities in African Americans,” a collaborative study by Cold Spring Harbor Laboratory, Weill Cornell Medicine, NewYork-Presbyterian Brooklyn Methodist Hospital, and Northwell Health. The aim is to establish an annotated biobank and create the necessary clinical and experimental frameworks to gain new insights about the endometrial cancer disparities in African Americans. Lead investigators include: Drs. Semir Beyaz, Hannah Meyer, Richard McCombie, Cold Spring Harbor Laboratory; Drs. Onyinye Balogun, Hani Ashamalla, Tan Ince, Margaux Kanis, Constantine Gorelick, NewYork-Presbyterian/Brooklyn Methodist; Dr. Wen Shen, Weill Cornell Medicine; Drs. Gary Goldberg, Marina Frimer, Aaron Nizam, Northwell Health.
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