| Title | Studies on the structure and possible function of the RNA "cap" in developing sea urchins. |
| Publication Type | Journal Article |
| Year of Publication | 1977 |
| Authors | Sconzo G, Roccheri MC, Di Liberto M, Giudice G |
| Journal | Cell Differ |
| Volume | 5 |
| Issue | 5-6 |
| Pagination | 323-34 |
| Date Published | 1977 Mar |
| ISSN | 0045-6039 |
| Keywords | Animals, Base Sequence, Dactinomycin, Embryo, Nonmammalian, Methylation, Nucleic Acid Conformation, RNA, Messenger, Sea Urchins |
| Abstract | Paracentrotus lividus embryos at the hatching blastula stage very quickly incorporate radioactivity from labeled nucleosides (except uridine) or 32P- or methyl-labeled methionine into a portion of the RNA that has been identified as a "cap". The most probable sequence of this cap is m7G (5') ppp (5')mAmpCp. A very active "capping" and methylation of the "cap" of preexisting RNA molecules was shown to occur at the blastula stage. |
| DOI | 10.1016/0045-6039(77)90070-7 |
| Alternate Journal | Cell Differ |
| PubMed ID | 856478 |
Related Faculty:
Maurizio DiLiberto, Ph.D.