Myeloid, mast cell, histiocytic and dendritic cell neoplasms and proliferations involving the spleen.

TitleMyeloid, mast cell, histiocytic and dendritic cell neoplasms and proliferations involving the spleen.
Publication TypeJournal Article
Year of Publication2021
AuthorsPrakash S, Padilla O, Tam W
JournalSemin Diagn Pathol
Volume38
Issue2
Pagination144-153
Date Published2021 Mar
ISSN0740-2570
Abstract

Splenic involvement and consequent splenomegaly are usually seen as part of systemic involvement by myeloid neoplasms as well as mast cell and histiocytic neoplasms. Primary splenic involvement by these neoplasms is rare. Splenectomy is usually not performed for establishing a diagnosis of these entities. However, in rare instances, the pathologist may need to evaluate the spleen secondary to splenic rupture or palliative splenectomy to alleviate symptoms related to splenomegaly. This review article describes the clinicopathologic features of a broad group of myeloid, mastocytic, and histiocytic proliferative and neoplastic disorders.

DOI10.1053/j.semdp.2020.07.003
Alternate JournalSemin Diagn Pathol
PubMed ID33012564
Related Faculty: 
Wayne Tam, M.D., Ph.D.

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