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Transfusion Medicine
The Transfusion Medicine Laboratory provides blood banking and transfusion testing services at NewYork-Presbyterian/Weill Cornell Medicine. The laboratory provides testing and expertise to identify factors in transfusion recipients that may increase their risk of reactions and complications. The primary goals are ensuring the safe use of blood products and the proper utilization of scarce resources. The laboratory is regulated under the U.S. Food and Drug Administration (FDA) and New York State Department of Health and is accredited by the College of American Pathologists (CAP) and AABB (formerly the American Association of Blood Banks). A quality assurance team within the service assures compliance with regulatory and accrediting agencies.
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Cellular Therapy
The Cellular Therapy Laboratory is part of the blood and marrow transplantation team at NewYork-Presbyterian/Weill Cornell. The laboratory is responsible for processing, testing, storing, and assisting with the infusion of cellular therapy products used for autologous and related and unrelated allogeneic transplantation. The laboratory is regulated under the U.S. Food and Drug Administration (FDA) and New York State Department of Health and accredited by the Foundation for the Accreditation of Cellular Therapy (FACT) and the College of American Pathologists (CAP). All services are performed in compliance with governmental regulations and national standards and guidelines, under the direction of the quality assurance team.
Processing encompasses procedures such as volume reduction, red cell and plasma reduction, washing of cells to remove cryoprotective media, and more complex procedures such as CD34 enrichment. Testing includes quantitative flow cytometry for CD34 and CD3 content, nucleated cell counts, and hematopoietic progenitor cell cultures on cell therapy products, as well as monitoring peripheral blood samples during mobilization to optimize apheresis collections.Â
Storage involves addition of cryoprotective media to products, followed by cryopreservation, and placement into the vapor phase in liquid nitrogen freezers. Cellular Therapy delivers cryopreserved or washed products to the recipient’s bedside (both inpatient and outpatient), and is responsible for thawing the cryopreserved specimens at the bedside and assisting with product infusion.
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Transfusion Medicine Consultative Services:
Research
Transfusion Medicine and Cellular Therapy Laboratory physicians also participate in research projects. Examples include:
Education
In addition, faculty members are involved in educational initiatives, including: