Faculty Publications

Tan Ince, MD, PhD

HDAC7 regulates histone 3 lysine 27 acetylation and transcriptional activity at super-enhancer-associated genes in breast cancer stem cells

Oncogene. 2019 Sep;38(39):6599-6614.

Caslini C, Hong S, Ban YJ, Chen XS, Ince TA.

PMID: 31375747

Tan Ince, MD, PhD

Ovarian Cancer Treatment Stratification Using Ex Vivo Drug Sensitivity Testing

Anticancer Res. 2019 Aug;39(8):4023-4030.

Lohse I, Azzam DJ, Al-Ali H, Volmar CH, Brothers SP, Ince TA, Wahlestedt C.

PMID: 31366484

Sabrina Racine-Brzostek, MD, PhD

The impact of Daratumumab on transfusion service costs

Transfusion. 2019 Apr;59(4):1252-1258.

Cushing MM, DeSimone RA, Goel R, Hsu YS, Parra P, Racine-Brzostek SE, Degtyaryova D, Lo DT, Morrison M, Crowley KM, Rossi A, Vasovic LV.

PMID: 30620407

Jorge Moscat, PhD

Increased Serine and One-Carbon Pathway Metabolism by PKCλ/ι Deficiency Promotes Neuroendocrine Prostate Cancer

Cancer Cell. 2019 Mar 18;35(3):385-400.

Reina-Campos M, Linares JF, Duran A, Cordes T, L'Hermitte A, Badur MG, Bhangoo MS, Thorson PK, Richards A, Rooslid T, Garcia-Olmo DC, Nam-Cha SY, Salinas-Sanchez AS, Eng K, Beltran H, Scott DA, Metallo CM, Moscat J, Diaz-Meco MT.  

PMID: 30827887; PMCID: PMC6424636

Maria Teresa Diaz-Meco Conde, PhD

Increased Serine and One-Carbon Pathway Metabolism by PKCλ/ι Deficiency Promotes Neuroendocrine Prostate Cancer.

Cancer Cell. 2019 Mar 18;35(3):385-400.

Reina-Campos M, Linares JF, Duran A, Cordes T, L'Hermitte A, Badur MG, Bhangoo MS, Thorson PK, Richards A, Rooslid T, Garcia-Olmo DC, Nam-Cha SY, Salinas-Sanchez AS, Eng K, Beltran H, Scott DA, Metallo CM, Moscat J, Diaz-Meco MT.

PMID: 30827887; PMCID: PMC6424636

Massimo Loda, MD

Genetic and Epigenetic Determinants of Aggressiveness in Cribriform Carcinoma of the Prostate

Mol Cancer Res. 2019 Feb;17(2):446-456.

Elfandy H, Armenia J, Pederzoli F, Pullman E, Pertega-Gomes N, Schultz N, Viswanathan K, Vosoughi A, Blattner M, Stopsack KH, Zadra G, Penney KL, Mosquera JM, Tyekucheva S, Mucci LA, Barbieri C, Loda M.

PMID: 30333152; PMCID: PMC6359952

Arryn Craney, PhD

Inhibition of Protein Secretion in Escherichia coli and Sub-MIC Effects of Arylomycin Antibiotics

Antimicrob Agents Chemother. 2019 Jan 29;63(2). pii: e01253-18.

Walsh SI, Peters DS, Smith PA, Craney A, Dix MM, Cravatt BF, Romesberg FE.

PMID: 30420476; PMCID: PMC6355593

Ok-Kyong Chaekal, MD

Cellular Therapy for Follicular Lymphoma

Chaekal O and van Besien K

Cellular Therapy for follicular lymphoma, in Follicular Lymphoma: Current Management and Novel Approaches

(Nathan H. Fowler, Editor). Springer (In Press)

Massimo Loda, MD

Inhibition of de novo lipogenesis targets androgen receptor signaling in castration-resistant prostate cancer

Proc Natl Acad Sci U S A. 2019 Jan 8;116(2):631-640. 

Zadra G, Ribeiro CF, Chetta P, Ho Y, Cacciatore S, Gao X, Syamala S, Bango C, Photopoulos C, Huang Y, Tyekucheva S, Bastos DC, Tchaicha J, Lawney B, Uo T, D'Anello L, Csibi A, Kalekar R, Larimer B, Ellis L, Butler LM, Morrissey C, McGovern K, Palombella VJ, Kutok JL, Mahmood U, Bosari S, Adams J, Peluso S, Dehm SM, Plymate SR, Loda M.

PMID: 30578319; PMCID: PMC6329966

Ok-Kyong Chaekal, MD

A renaissance for autologous transplantation in follicular lymphoma?

Leuk Lymphoma. 2019 Jan;60(1):3-5.

Chaekal OK, van Besien K.

PMID: 29966478

Massimo Loda, MD

Expression of IGF/insulin receptor in prostate cancer tissue and progression to lethal disease

Carcinogenesis. 2018 Dec 31;39(12):1431-1437. 

Ahearn TU, Peisch S, Pettersson A, Ebot EM, Zhou CK, Graff RE, Sinnott JA, Fazli L, Judson GL, Bismar TA, Rider JR, Gerke T, Chan JM, Fiorentino M, Flavin R, Sesso HD, Finn S, Giovannucci EL, Gleave M, Loda M, Li Z, Pollak M, Mucci LA; Transdisciplinary Prostate Cancer Partnership (ToPCaP).

PMID: 30165429; PMCID: PMC6314328

Jorge Moscat, PhD

Simultaneous Loss of Both Atypical Protein Kinase C Genes in the Intestinal Epithelium Drives Serrated Intestinal Cancer by Impairing Immunosurveillance

Immunity. 2018 Dec 18;49(6):1132-1147.e7.

Nakanishi Y, Duran A, L'Hermitte A, Shelton PM, Nakanishi N, Reina-Campos M, Huang J, Soldevila F, Baaten BJG, Tauriello DVF, Castilla EA, Bhangoo MS, Bao F, Sigal D, Diaz-Meco MT, Moscat J.

PMID: 30552022; PMCID: PMC6301096

Massimo Loda, MD

Transcriptome Deconvolution of Heterogeneous Tumor Samples with Immune Infiltration

iScience. 2018 Nov 30;9:451-460.

Wang Z, Cao S, Morris JS, Ahn J, Liu R, Tyekucheva S, Gao F, Li B, Lu W, Tang X, Wistuba II, Bowden M, Mucci L, Loda M, Parmigiani G, Holmes CC, Wang W.

PMID: 30469014; PMCID: PMC6249353

Tan Ince, MD, PhD

Dual Src and MEK Inhibition Decreases Ovarian Cancer Growth and Targets Tumor Initiating Stem-Like Cells

Clin Cancer Res. 2018 Oct 1;24(19):4874-4886. 

Simpkins F, Jang K, Yoon H, Hew KE, Kim M, Azzam DJ, Sun J, Zhao D, Ince TA, Liu W, Guo W, Wei Z, Zhang G, Mills GB, Slingerland JM.

PMID: 29959144; PMCID: PMC6557165

Massimo Loda, MD

A Prospective Study of Aspirin Use and Prostate Cancer Risk by TMPRSS2:ERG Status.

Cancer Epidemiol Biomarkers Prev. 2018 Oct;27(10):1231-1233.

Stopsack KH, Gonzalez-Feliciano AG, Peisch SF, Downer MK, Gage RA, Finn S, Lis RT, Graff RE, Pettersson A, Pernar CH, Loda M, Kantoff PW, Ahearn TU, Mucci LA; Transdisciplinary Prostate Cancer Partnership (ToPCaP).

PMID: 30108097; PMCID: PMC6170677

Seung Ha (Anna) Nam, MD

Surf4 (Erv29p) binds amino-terminal tripeptide motifs of soluble cargo proteins with different affinities, enabling prioritization of their exit from the endoplasmic reticulum

PLoS Biol. 2018 Aug 7;16(8):e2005140.

Yin Y, Garcia MR, Novak AJ, Saunders AM, Ank RS, Nam AS, Fisher LW.

PMID: 30086131; PMCID: PMC6097701

Nina Schatz-Siemers, DO

Napsin-A Positivity in Clear Cell and Gastric-Type Carcinoma of the Uterine Cervix

Submitted to Applied Immunohistochemistry and Molecular Morphology

Schatz-Siemers N, Sung D, Matrai C, Ellenson LH, Pirog EC.

Benjamin L. Liechty, MD

Loss of histone H3K27me3 identifies a subset of meningiomas with increased risk of recurrence

Acta Neuropathol. 2018 Jun;135(6):955-963. 

Katz LM, Hielscher T, Liechty B, Silverman J, Zagzag D, Sen R, Wu P, Golfinos JG, Reuss D, Neidert MC, Wirsching HG, Baumgarten P, Herold-Mende C, Wick W, Harter PN, Weller M, von Deimling A, Snuderl M, Sen C, Sahm F.

PMID: 29627952

Tan Ince, MD, PhD

Label and Immobilization Free Detection and Differentiation of Tumor Cells

IEEE Sensors Journal: Volume: 18 , Issue: 9 , May, 1 2018

Gajasinghe R, Jones M, Ince TA and Tigli O.

Benjamin L. Liechty, MD

Programmed death ligand 1 expression and tumor infiltrating lymphocytes in neurofibromatosis type 1 and 2 associated tumors

J Neurooncol. 2018 May;138(1):183-190. 

Wang S, Liechty B, Patel S, Weber JS, Hollmann TJ, Snuderl M, Karajannis MA.

PMID: 29427150; PMCID: PMC5930071