Faculty Publications

Luigi Marchionni, MD, PhD

Influenza Vaccination and COVID-19 Mortality in the USA: An Ecological Study

Vaccines (Basel). 2021 Apr 24;9(5):427. 

Zanettini C, Omar M, Dinalankara W, Imada EL, Colantuoni E, Parmigiani G, Marchionni L.

PMID: 33923159

He Sarina Yang, PhD, Zhen Zhao, PhD

Sensitive tracking of circulating viral RNA through all stages of SARS-CoV-2 infection

J Clin Invest. 2021 Apr 1;131(7):e146031.

Huang Z, Ning B, Yang HS, Youngquist BM, Niu A, Lyon CJ, Beddingfield BJ, Fears AC, Monk CH, Murrell AE, Bilton SJ, Linhuber JP, Norton EB, Dietrich ML, Yee J, Lai W, Scott JW, Yin XM, Rappaport J, Robinson JE, Saba NS, Roy CJ, Zwezdaryk KJ, Zhao Z, Hu TY.

PMID: 33561010; PMCID: PMC8011898

Steven P. Salvatore, MD, Alain Borczuk, MD

The spatial landscape of lung pathology during COVID-19 progression

Nature. 2021 Mar 29. 

Rendeiro AF, Ravichandran H, Bram Y, Chandar V, Kim J, Meydan C, Park J, Foox J, Hether T, Warren S, Kim Y, Reeves J, Salvatore S, Mason CE, Swanson EC, Borczuk AC, Elemento O, Schwartz RE.

PMID: 33780969

Arryn Craney, PhD, Priya Velu, MD, PhD, Alain Borczuk, MD, Massimo Loda, MD, Lars Westblade, PhD, Melissa Cushing, MD, Hanna Rennert, PhD, Marcin Imielinski, MD, PhD

Shotgun transcriptome, spatial omics, and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug interactions

Nat Commun. 2021 Mar 12;12(1):1660. 

Butler D, Mozsary C, Meydan C, Foox J, Rosiene J, Shaiber A, Danko D, Afshinnekoo E, MacKay M, Sedlazeck FJ, Ivanov NA, Sierra M, Pohle D, Zietz M, Gisladottir U, Ramlall V, Sholle ET, Schenck EJ, Westover CD, Hassan C, Ryon K, Young B, Bhattacharya C, Ng DL, Granados AC, Santos YA, Servellita V, Federman S, Ruggiero P, Fungtammasan A, Chin CS, Pearson NM, Langhorst BW, Tanner NA, Kim Y, Reeves JW, Hether TD, Warren SE, Bailey M, Gawrys J, Meleshko D, Xu D, Couto-Rodriguez M, Nagy-Szakal D, Barrows J, Wells H, O'Hara NB, Rosenfeld JA, Chen Y, Steel PAD, Shemesh AJ, Xiang J, Thierry-Mieg J, Thierry-Mieg D, Iftner A, Bezdan D, Sanchez E, Campion TR Jr, Sipley J, Cong L, Craney A, Velu P, Melnick AM, Shapira S, Hajirasouliha I, Borczuk A, Iftner T, Salvatore M, Loda M, Westblade LF, Cushing M, Wu S, Levy S, Chiu C, Schwartz RE, Tatonetti N, Rennert H, Imielinski M, Mason CE.

PMID: 33712587; PMCID: PMC7954844

Paul Simonson, MD, PhD

Hospitalization and mortality associated with SARS-CoV-2 viral clades in COVID-19

Sci Rep. 2021 Feb 26;11(1):4802. 

Nakamichi K, Shen JZ, Lee CS, Lee A, Roberts EA, Simonson PD, Roychoudhury P, Andriesen J, Randhawa AK, Mathias PC, Greninger AL, Jerome KR, Van Gelder RN.

PMID: 33637820; PMCID: PMC7910290

Sabrina Racine-Brzostek, MD, PhD, Amy Chadburn, MD, He Sarina Yang, PhD, Melissa Cushing, MD, Zhen Zhao, PhD

TOP-Plus is a Versatile Biosensor Platform for Monitoring SARS-CoV-2 Antibody Durability

medRxiv [Preprint]. 2021 Feb 8:2021.02.03.21251089.

Racine-Brzostek SE, Karbaschi M, Gaebler C, Klasse PJ, Yee J, Caskey M, Yang HS, Hao Y, Chadburn A, Shi Y, Zuk R, Nussenzweig MC, Cushing MM, Zhao Z.

PMID: 33564790; PMCID: PMC7872385

Sabrina Racine-Brzostek, MD, PhD, He Sarina Yang, PhD, Amy Chadburn, MD, Melissa Cushing, MD, Zhen Zhao, PhD

Post Convalescent SARS-CoV-2 IgG and Neutralizing Antibodies Are Elevated in Individuals with Poor Metabolic Health

J Clin Endocrinol Metab. 2021 Feb 1:dgab004. Epub ahead of print. 

Racine-Brzostek SE, Yang HS, Jack GA, Chen Z, Chadburn A, Ketas TJ, Francomano E, Klasse PJ, Moore JP, McDonough KA, Girardin RC, Dupuis Ii AP, Payne AF, Ma L, Sweeney J, Zhong E, Yee J, Cushing MM, Zhao Z. 

PMID: 33524125

Yawei (Jenny) Yang, MD, PhD, Zhen Zhao, PhD

Severe acute respiratory syndrome coronavirus 2 serology levels in pregnant women and their neonates

Am J Obstet Gynecol. 2021 Jan 23:S0002-9378(21)00053-3. 

Kubiak JM, Murphy EA, Yee J, Cagino KA, Friedlander RL, Glynn SM, Matthews KC, Jurkiewicz M, Sukhu AC, Zhao Z, Prabhu M, Riley LE, Yang YJ.

PMID: 33497654; PMCID: PMC7825873

He Sarina Yang, PhD, Sabrina Racine-Brzostek, MD, PhD, Lars Westblade, PhD, Melissa Cushing, MD, Amy Chadburn, MD, Zhen Zhao, PhD

Testing-on-a-probe biosensors reveal association of early SARS-CoV-2 total antibodies and surrogate neutralizing antibodies with mortality in COVID-19 patients

Biosens Bioelectron. 2021 Jan 20;178:113008.

Yang HS, Racine-Brzostek SE, Karbaschi M, Yee J, Dillard A, Steel PAD, Lee WT, McDonough KA, Qiu Y, Ketas TJ, Francomano E, Klasse PJ, Hatem L, Westblade L, Wu H, Chen H, Zuk R, Tan H, Girardin RC, Dupuis AP 2nd, Payne AF, Moore JP, Cushing MM, Chadburn A, Zhao Z.

PMID: 33515984; PMCID: PMC7816890

Zhen Zhao, PhD

Evolution of antibody immunity to SARS-CoV-2

Nature. 2021 Jan 18. Epub ahead of print.

Gaebler C, Wang Z, Lorenzi JCC, Muecksch F, Finkin S, Tokuyama M, Cho A, Jankovic M, Schaefer-Babajew D, Oliveira TY, Cipolla M, Viant C, Barnes CO, Bram Y, Breton G, Hägglöf T, Mendoza P, Hurley A, Turroja M, Gordon K, Millard KG, Ramos V, Schmidt F, Weisblum Y, Jha D, Tankelevich M, Martinez-Delgado G, Yee J, Patel R, Dizon J, Unson-O'Brien C, Shimeliovich I, Robbiani DF, Zhao Z, Gazumyan A, Schwartz RE, Hatziioannou T, Bjorkman PJ, Mehandru S, Bieniasz PD, Caskey M, Nussenzweig MC.

PMID: 33461210.

Priya Velu, MD, PhD, Arryn Craney, PhD, Massimo Loda, MD, Lars Westblade, PhD, Melissa Cushing, MD, Hanna Rennert, PhD

Rapid Implementation of Severe Acute Respiratory Syndrome Coronavirus 2 Emergency Use Authorization RT-PCR Testing and Experience at an Academic Medical Institution

J Mol Diagn. 2020 Dec 5:S1525-1578(20)30582-1. 

Velu P, Craney A, Ruggiero P, Sipley J, Cong L, Hissong EM, Loda M, Westblade LF, Cushing M, Rennert H. 

PMID: 33285285; PMCID: PMC7718583

Surya V. Seshan, MD, Cynthia M. Magro, MD, Steven P. Salvatore, MD

Docked severe acute respiratory syndrome coronavirus 2 proteins within the cutaneous and subcutaneous microvasculature and their role in the pathogenesis of severe coronavirus disease 2019

Hum Pathol. 2020 Dec;106:106-116.

Magro CM, Mulvey JJ, Laurence J, Seshan S, Crowson AN, Dannenberg AJ, Salvatore S, Harp J, Nuovo GJ.

PMID: 33058948; PMCID: PMC7550120

Robert DeSimone, MD, Paul Simonson, MD, PhD, Steven P. Salvatore, MD, Giorgio Inghirami, MD

Profiling of immune dysfunction in COVID-19 patients allows early prediction of disease progression

Life Sci Alliance. 2020 Dec 24;4(2):e202000955.

Rendeiro AF, Casano J, Vorkas CK, Singh H, Morales A, DeSimone RA, Ellsworth GB, Soave R, Kapadia SN, Saito K, Brown CD, Hsu J, Kyriakides C, Chiu S, Cappelli LV, Cacciapuoti MT, Tam W, Galluzzi L, Simonson PD, Elemento O, Salvatore M, Inghirami G.

PMID: 33361110; PMCID: PMC7768198

Lars Westblade, PhD

Clinical performance of the point-of-care cobas Liat for detection of SARS-CoV-2 in 20 minutes: A multicenter study

J Clin Microbiol. 2020 Nov 25:JCM.02811-20. 

Hansen G, Marino J, Wang ZX, Beavis KG, Rodrigo J, Labog K, Westblade LF, Jin R, Love N, Ding K, Garg S, Huang A, Sickler J, Tran NK. 

PMID: 33239382

Robert DeSimone, MD, Melissa Cushing, MD

Blood component utilization in COVID-19 patients in New York City: Transfusions do not follow the curve

Transfusion. 2020 Nov 20. 

DeSimone RA, Costa VA, Kane K, Sepulveda JL, Ellsworth GB, Gulick RM, Zucker J, Sobieszcyk ME, Schwartz J, Cushing MM.

PMID: 33215718.

Alain Borczuk, MD

SARS-CoV-2 Infected Cardiomyocytes Recruit Monocytes by Secreting CCL2

Res Sq [Preprint]. 2020 Nov 17:rs.3.rs-94634. 

Chen S, Yang L, Nilsson-Payant B, Han Y, Jaffré F, Zhu J, Wang P, Zhang T, Redmond D, Houghton S, Møller R, Hoagland D, Horiuchi S, Acklin J, Lim J, Bram Y, Richardson C, Chandar V, Borczuk A, Huang Y, Xiang J, Ho D, Schwartz R, tenOever B, Evans T.

PMID: 33236003; PMCID: PMC7685325.

Lars Westblade, PhD, Melissa Cushing, MD, Massimo Loda, MD, Jacob H. Rand, MD

SARS-CoV-2 Viral Load Predicts Mortality in Patients with and without Cancer Who Are Hospitalized with COVID-19

Cancer Cell. 2020 Nov 9;38(5):661-671.e2. 

Westblade LF, Brar G, Pinheiro LC, Paidoussis D, Rajan M, Martin P, Goyal P, Sepulveda JL, Zhang L, George G, Liu D, Whittier S, Plate M, Small CB, Rand JH, Cushing MM, Walsh TJ, Cooke J, Safford MM, Loda M, Satlin MJ.

PMID: 32997958; PMCID: PMC7492074

He Sarina Yang, PhD, Ljiljana Vasovic, MD, Amy Chadburn, MD, Sabrina Racine-Brzostek, MD, PhD, Priya Velu, MD, PhD, Melissa Cushing, MD, Massimo Loda, MD, Zhen Zhao, PhD

Routine Laboratory Blood Tests Predict SARS-CoV-2 Infection Using Machine Learning

Clin Chem. 2020 Nov 1;66(11):1396-1404.

Yang HS, Hou Y, Vasovic LV, Steel PAD, Chadburn A, Racine-Brzostek SE, Velu P, Cushing MM, Loda M, Kaushal R, Zhao Z, Wang F.

PMID: 32821907; PMCID: PMC7499540

The interpretation of high-grade squamous intraepithelial lesion on anal cytology: a comparative analysis with the cervical Papanicolaou test

J Am Soc Cytopathol. 2020 Nov-Dec;9(6):540-549. 

Patel AP, Schatz-Siemers NF, Dilcher TL, Goyal A.

PMID: 32800528

Interobserver variability between cytopathologists and cytotechnologists upon application and characterization of the indeterminate category in the Milan System for Reporting Salivary Gland Cytopathology

Cancer Cytopathol. 2020 Nov;128(11):828-839. 

Viswanathan K, Patel A, Abdelsayed M, Rosado L, Soong L, Margolskee E, Heymann JJ, Goyal A, Rao RA.

PMID: 32573971