Faculty Publications

Sabrina Racine-Brzostek, MD, PhD, He Sarina Yang, PhD, Amy Chadburn, MD, Melissa Cushing, MD, Zhen Zhao, PhD

Post Convalescent SARS-CoV-2 IgG and Neutralizing Antibodies Are Elevated in Individuals with Poor Metabolic Health

J Clin Endocrinol Metab. 2021 Feb 1:dgab004. Epub ahead of print. 

Racine-Brzostek SE, Yang HS, Jack GA, Chen Z, Chadburn A, Ketas TJ, Francomano E, Klasse PJ, Moore JP, McDonough KA, Girardin RC, Dupuis Ii AP, Payne AF, Ma L, Sweeney J, Zhong E, Yee J, Cushing MM, Zhao Z. 

PMID: 33524125

He Sarina Yang, PhD, Sabrina Racine-Brzostek, MD, PhD, Lars Westblade, PhD, Melissa Cushing, MD, Amy Chadburn, MD, Zhen Zhao, PhD

Testing-on-a-probe biosensors reveal association of early SARS-CoV-2 total antibodies and surrogate neutralizing antibodies with mortality in COVID-19 patients

Biosens Bioelectron. 2021 Jan 20;178:113008.

Yang HS, Racine-Brzostek SE, Karbaschi M, Yee J, Dillard A, Steel PAD, Lee WT, McDonough KA, Qiu Y, Ketas TJ, Francomano E, Klasse PJ, Hatem L, Westblade L, Wu H, Chen H, Zuk R, Tan H, Girardin RC, Dupuis AP 2nd, Payne AF, Moore JP, Cushing MM, Chadburn A, Zhao Z.

PMID: 33515984; PMCID: PMC7816890

Zhen Zhao, PhD

Evolution of antibody immunity to SARS-CoV-2

Nature. 2021 Jan 18. Epub ahead of print.

Gaebler C, Wang Z, Lorenzi JCC, Muecksch F, Finkin S, Tokuyama M, Cho A, Jankovic M, Schaefer-Babajew D, Oliveira TY, Cipolla M, Viant C, Barnes CO, Bram Y, Breton G, Hägglöf T, Mendoza P, Hurley A, Turroja M, Gordon K, Millard KG, Ramos V, Schmidt F, Weisblum Y, Jha D, Tankelevich M, Martinez-Delgado G, Yee J, Patel R, Dizon J, Unson-O'Brien C, Shimeliovich I, Robbiani DF, Zhao Z, Gazumyan A, Schwartz RE, Hatziioannou T, Bjorkman PJ, Mehandru S, Bieniasz PD, Caskey M, Nussenzweig MC.

PMID: 33461210.

Priya Velu, MD, PhD, Arryn Craney, PhD, Massimo Loda, MD, Lars Westblade, PhD, Melissa Cushing, MD, Hanna Rennert, PhD

Rapid Implementation of Severe Acute Respiratory Syndrome Coronavirus 2 Emergency Use Authorization RT-PCR Testing and Experience at an Academic Medical Institution

J Mol Diagn. 2020 Dec 5:S1525-1578(20)30582-1. 

Velu P, Craney A, Ruggiero P, Sipley J, Cong L, Hissong EM, Loda M, Westblade LF, Cushing M, Rennert H. 

PMID: 33285285; PMCID: PMC7718583

Lars Westblade, PhD

Clinical performance of the point-of-care cobas Liat for detection of SARS-CoV-2 in 20 minutes: A multicenter study

J Clin Microbiol. 2020 Nov 25:JCM.02811-20. 

Hansen G, Marino J, Wang ZX, Beavis KG, Rodrigo J, Labog K, Westblade LF, Jin R, Love N, Ding K, Garg S, Huang A, Sickler J, Tran NK. 

PMID: 33239382

Robert DeSimone, MD, Melissa Cushing, MD

Blood component utilization in COVID-19 patients in New York City: Transfusions do not follow the curve

Transfusion. 2020 Nov 20. 

DeSimone RA, Costa VA, Kane K, Sepulveda JL, Ellsworth GB, Gulick RM, Zucker J, Sobieszcyk ME, Schwartz J, Cushing MM.

PMID: 33215718.

Alain Borczuk, MD

SARS-CoV-2 Infected Cardiomyocytes Recruit Monocytes by Secreting CCL2

Res Sq [Preprint]. 2020 Nov 17:rs.3.rs-94634. 

Chen S, Yang L, Nilsson-Payant B, Han Y, Jaffré F, Zhu J, Wang P, Zhang T, Redmond D, Houghton S, Møller R, Hoagland D, Horiuchi S, Acklin J, Lim J, Bram Y, Richardson C, Chandar V, Borczuk A, Huang Y, Xiang J, Ho D, Schwartz R, tenOever B, Evans T.

PMID: 33236003; PMCID: PMC7685325.

Lars Westblade, PhD, Melissa Cushing, MD, Massimo Loda, MD, Jacob H. Rand, MD

SARS-CoV-2 Viral Load Predicts Mortality in Patients with and without Cancer Who Are Hospitalized with COVID-19

Cancer Cell. 2020 Nov 9;38(5):661-671.e2. 

Westblade LF, Brar G, Pinheiro LC, Paidoussis D, Rajan M, Martin P, Goyal P, Sepulveda JL, Zhang L, George G, Liu D, Whittier S, Plate M, Small CB, Rand JH, Cushing MM, Walsh TJ, Cooke J, Safford MM, Loda M, Satlin MJ.

PMID: 32997958; PMCID: PMC7492074

Cynthia M. Magro, MD

Concomitant calciphylaxis and COVID-19 associated thrombotic retiform purpura

Skeletal Radiol. 2020 Nov;49(11):1879-1884.

Rotman JA, Dean KE, Magro C, Nuovo G, Bartolotta RJ.

PMID: 32844243; PMCID: PMC7447529

Alain Borczuk, MD, Steven P. Salvatore, MD, Surya V. Seshan, MD, Sanjay Patel, MD, MPH

COVID-19 pulmonary pathology: a multi-institutional autopsy cohort from Italy and New York City

Mod Pathol. 2020 Nov;33(11):2156-2168. 

Borczuk AC, Salvatore SP, Seshan SV, Patel SS, Bussel JB, Mostyka M, Elsoukkary S, He B, Del Vecchio C, Fortarezza F, Pezzuto F, Navalesi P, Crisanti A, Fowkes ME, Bryce CH, Calabrese F, Beasley MB.

PMID: 32879413; PMCID: PMC7463226

He Sarina Yang, PhD, Ljiljana Vasovic, MD, Amy Chadburn, MD, Sabrina Racine-Brzostek, MD, PhD, Priya Velu, MD, PhD, Melissa Cushing, MD, Massimo Loda, MD, Zhen Zhao, PhD

Routine Laboratory Blood Tests Predict SARS-CoV-2 Infection Using Machine Learning

Clin Chem. 2020 Nov 1;66(11):1396-1404.

Yang HS, Hou Y, Vasovic LV, Steel PAD, Chadburn A, Racine-Brzostek SE, Velu P, Cushing MM, Loda M, Kaushal R, Zhao Z, Wang F.

PMID: 32821907; PMCID: PMC7499540

Jose Jessurun, MD, Alain Borczuk, MD

Identification of SARS-CoV-2 inhibitors using lung and colonic organoids

Nature. 2020 Oct 28.

Han Y, Duan X, Yang L, Nilsson-Payant BE, Wang P, Duan F, Tang X, Yaron TM, Zhang T, Uhl S, Bram Y, Richardson C, Zhu J, Zhao Z, Redmond D, Houghton S, Nguyen DT, Xu D, Wang X, Jessurun J, Borczuk A, Huang Y, Johnson JL, Liu Y, Xiang J, Wang H, Cantley LC, tenOever BR, Ho DD, Pan FC, Evans T, Chen HJ, Schwartz RE, Chen S.

PMID: 33116299

Steven P. Salvatore, MD, Alain Borczuk, MD

The spatio-temporal landscape of lung pathology in SARS-CoV-2 infection

medRxiv [Preprint]. 2020 Oct 27:2020.10.26.20219584.

Rendeiro AF, Ravichandran H, Bram Y, Salvatore S, Borczuk A, Elemento O, Schwartz RE.

PMID: 33140072; PMCID: PMC7605585

Cynthia M. Magro, MD

Strong homology between SARS-CoV-2 envelope protein and a Mycobacterium sp. antigen allows rapid diagnosis of Mycobacterial infections and may provide specific anti-SARS-CoV-2 immunity via the BCG vaccine

Ann Diagn Pathol. 2020 Oct;48:151600. 

Nuovo G, Tili E, Suster D, Matys E, Hupp L, Magro C.

PMID: 32805515; PMCID: PMC7423587

He Sarina Yang, PhD, Sabrina Racine-Brzostek, MD, PhD, Amy Chadburn, MD, Lars Westblade, PhD, Massimo Loda, MD, Melissa Cushing, MD, Zhen Zhao, PhD

SARS-CoV-2 antibody characterization in emergency department, hospitalized and convalescent patients by two semi-quantitative immunoassays

Clin Chim Acta. 2020 Oct;509:117-125. 

Yang HS, Racine-Brzostek SE, Lee WT, Hunt D, Yee J, Chen Z, Kubiak J, Cantu M, Hatem L, Zhong E, D'Ambrosio D, Chadburn A, Westblade L, Glesby M, Loda M, Cushing MM, Zhao Z.

PMID: 32505774; PMCID: PMC7272145

Cynthia M. Magro, MD

Anti-complement C5 therapy with eculizumab in three cases of critical COVID-19

Clin Immunol. 2020 Oct;219:108555.

Laurence J, Mulvey JJ, Seshadri M, Racanelli A, Harp J, Schenck EJ, Zappetti D, Horn EM, Magro CM. 

PMID: 32771488; PMCID: PMC7410014

Amy Chadburn, MD, Rhonda K. Yantiss, MD, Jose Jessurun, MD, Surya V. Seshan, MD, Alain Borczuk, MD, Steven P. Salvatore, MD

Autopsy Findings in 32 Patients with COVID-19: A Single-Institution Experience

Pathobiology. 2020 Sep 17:1-13. 

Elsoukkary SS, Mostyka M, Dillard A, Berman DR, Ma LX, Chadburn A, Yantiss RK, Jessurun J, Seshan SV, Borczuk AC, Salvatore SP.

PMID: 32942274; PMCID: PMC7573917

Robert DeSimone, MD, Giorgio Inghirami, MD

Longitudinal immune profiling of mild and severe COVID-19 reveals innate and adaptive immune dysfunction and provides an early prediction tool for clinical progression

medRxiv [Preprint]. 2020 Sep 9:2020.09.08.20189092. 

Rendeiro AF, Casano J, Vorkas CK, Singh H, Morales A, DeSimone RA, Ellsworth GB, Soave R, Kapadia SN, Saito K, Brown CD, Hsu J, Kyriakides C, Chui S, Cappelli L, Cacciapuoti MT, Tam W, Galluzzi L, Simonson PD, Elemento O, Salvatore M, Inghirami G.

PMID: 32935114; PMCID: PMC7491529

Melissa Cushing, MD

Clinical Screening for COVID-19 in Asymptomatic Patients With Cancer

JAMA Netw Open. 2020 Sep 1;3(9):e2023121. 

Shah MA, Mayer S, Emlen F, Sholle E, Christos P, Cushing M, Hidalgo M.

PMID: 32990737; PMCID: PMC7525345

Cynthia M. Magro, MD

Livedoid and Purpuric Skin Eruptions Associated With Coagulopathy in Severe COVID-19

JAMA Dermatol. 2020 Sep 1;156(9):1-3. 

Droesch C, Do MH, DeSancho M, Lee EJ, Magro C, Harp J.

PMID: 32756881; PMCID: PMC7376463