Faculty Publications

Maria Teresa Diaz-Meco Conde, PhD, Jorge Moscat, PhD

The complexity of the serine glycine one-carbon pathway in cancer.

J Cell Biol. 2020 Jan 6;219(1).

Reina-Campos M, Diaz-Meco MT, Moscat J.

PMID: 31690618

Jorge Moscat, PhD

Serrated Colorectal Cancer: The Road Less Travelled?

Trends Cancer. 2019 Nov;5(11):742-754.

Nakanishi Y, Diaz-Meco MT, Moscat J.

PMID: 31735291; PMCID: PMC6894428

Maria Teresa Diaz-Meco Conde, PhD, Jorge Moscat, PhD

The Dual Roles of the Atypical Protein Kinase Cs in Cancer

Cancer Cell. 2019 Sep 16;36(3):218-235. 

Reina-Campos M, Diaz-Meco MT, Moscat J.

PMID: 31474570; PMCID: PMC6751000

Tan Ince, MD, PhD

HDAC7 regulates histone 3 lysine 27 acetylation and transcriptional activity at super-enhancer-associated genes in breast cancer stem cells

Oncogene. 2019 Sep;38(39):6599-6614.

Caslini C, Hong S, Ban YJ, Chen XS, Ince TA.

PMID: 31375747

Tan Ince, MD, PhD

Ovarian Cancer Treatment Stratification Using Ex Vivo Drug Sensitivity Testing

Anticancer Res. 2019 Aug;39(8):4023-4030.

Lohse I, Azzam DJ, Al-Ali H, Volmar CH, Brothers SP, Ince TA, Wahlestedt C.

PMID: 31366484

Sabrina Racine-Brzostek, MD, PhD

The impact of Daratumumab on transfusion service costs

Transfusion. 2019 Apr;59(4):1252-1258.

Cushing MM, DeSimone RA, Goel R, Hsu YS, Parra P, Racine-Brzostek SE, Degtyaryova D, Lo DT, Morrison M, Crowley KM, Rossi A, Vasovic LV.

PMID: 30620407

Jorge Moscat, PhD

Increased Serine and One-Carbon Pathway Metabolism by PKCλ/ι Deficiency Promotes Neuroendocrine Prostate Cancer

Cancer Cell. 2019 Mar 18;35(3):385-400.

Reina-Campos M, Linares JF, Duran A, Cordes T, L'Hermitte A, Badur MG, Bhangoo MS, Thorson PK, Richards A, Rooslid T, Garcia-Olmo DC, Nam-Cha SY, Salinas-Sanchez AS, Eng K, Beltran H, Scott DA, Metallo CM, Moscat J, Diaz-Meco MT.  

PMID: 30827887; PMCID: PMC6424636

Maria Teresa Diaz-Meco Conde, PhD

Increased Serine and One-Carbon Pathway Metabolism by PKCλ/ι Deficiency Promotes Neuroendocrine Prostate Cancer.

Cancer Cell. 2019 Mar 18;35(3):385-400.

Reina-Campos M, Linares JF, Duran A, Cordes T, L'Hermitte A, Badur MG, Bhangoo MS, Thorson PK, Richards A, Rooslid T, Garcia-Olmo DC, Nam-Cha SY, Salinas-Sanchez AS, Eng K, Beltran H, Scott DA, Metallo CM, Moscat J, Diaz-Meco MT.

PMID: 30827887; PMCID: PMC6424636

Massimo Loda, MD

Genetic and Epigenetic Determinants of Aggressiveness in Cribriform Carcinoma of the Prostate

Mol Cancer Res. 2019 Feb;17(2):446-456.

Elfandy H, Armenia J, Pederzoli F, Pullman E, Pertega-Gomes N, Schultz N, Viswanathan K, Vosoughi A, Blattner M, Stopsack KH, Zadra G, Penney KL, Mosquera JM, Tyekucheva S, Mucci LA, Barbieri C, Loda M.

PMID: 30333152; PMCID: PMC6359952

Arryn Craney, PhD

Inhibition of Protein Secretion in Escherichia coli and Sub-MIC Effects of Arylomycin Antibiotics

Antimicrob Agents Chemother. 2019 Jan 29;63(2). pii: e01253-18.

Walsh SI, Peters DS, Smith PA, Craney A, Dix MM, Cravatt BF, Romesberg FE.

PMID: 30420476; PMCID: PMC6355593

Ok-Kyong Chaekal, MD

Cellular Therapy for Follicular Lymphoma

Chaekal O and van Besien K

Cellular Therapy for follicular lymphoma, in Follicular Lymphoma: Current Management and Novel Approaches

(Nathan H. Fowler, Editor). Springer (In Press)

Jorge Moscat, PhD

p62/SQSTM1 Fuels Melanoma Progression by Opposing mRNA Decay of a Selective Set of Pro-metastatic Factors

Cancer Cell. 2019 Jan 14;35(1):46-63.

Karras P, Riveiro-Falkenbach E, Cañón E, Tejedo C, Calvo TG, Martínez-Herranz R, Alonso-Curbelo D, Cifdaloz M, Perez-Guijarro E, Gómez-López G, Ximenez-Embun P, Muñoz J, Megias D, Olmeda D, Moscat J, Ortiz-Romero PL, Rodríguez-Peralto JL, Soengas MS.

PMID: 30581152

Massimo Loda, MD

Inhibition of de novo lipogenesis targets androgen receptor signaling in castration-resistant prostate cancer

Proc Natl Acad Sci U S A. 2019 Jan 8;116(2):631-640. 

Zadra G, Ribeiro CF, Chetta P, Ho Y, Cacciatore S, Gao X, Syamala S, Bango C, Photopoulos C, Huang Y, Tyekucheva S, Bastos DC, Tchaicha J, Lawney B, Uo T, D'Anello L, Csibi A, Kalekar R, Larimer B, Ellis L, Butler LM, Morrissey C, McGovern K, Palombella VJ, Kutok JL, Mahmood U, Bosari S, Adams J, Peluso S, Dehm SM, Plymate SR, Loda M.

PMID: 30578319; PMCID: PMC6329966

Maria Teresa Diaz-Meco Conde, PhD

The signaling axis atypical protein kinase C λ/ι-Satb2 mediates leukemic transformation of B-cell progenitors

Nat Commun. 2019 Jan 4;10(1):46.

Nayak RC, Hegde S, Althoff MJ, Wellendorf AM, Mohmoud F, Perentesis J, Reina-Campos M, Reynaud D, Zheng Y, Diaz-Meco MT, Moscat J, Cancelas JA.

PMID: 30610188; PMCID: PMC6320370

Jorge Moscat, PhD

The signaling axis atypical protein kinase C λ/ι-Satb2 mediates leukemic transformation of B-cell progenitors

Nat Commun. 2019 Jan 4;10(1):46.

Nayak RC, Hegde S, Althoff MJ, Wellendorf AM, Mohmoud F, Perentesis J, Reina-Campos M, Reynaud D, Zheng Y, Diaz-Meco MT, Moscat J, Cancelas JA.

PMID: 30610188; PMCID: PMC6320370

Ok-Kyong Chaekal, MD

A renaissance for autologous transplantation in follicular lymphoma?

Leuk Lymphoma. 2019 Jan;60(1):3-5.

Chaekal OK, van Besien K.

PMID: 29966478

Massimo Loda, MD

Expression of IGF/insulin receptor in prostate cancer tissue and progression to lethal disease

Carcinogenesis. 2018 Dec 31;39(12):1431-1437. 

Ahearn TU, Peisch S, Pettersson A, Ebot EM, Zhou CK, Graff RE, Sinnott JA, Fazli L, Judson GL, Bismar TA, Rider JR, Gerke T, Chan JM, Fiorentino M, Flavin R, Sesso HD, Finn S, Giovannucci EL, Gleave M, Loda M, Li Z, Pollak M, Mucci LA; Transdisciplinary Prostate Cancer Partnership (ToPCaP).

PMID: 30165429; PMCID: PMC6314328

Maria Teresa Diaz-Meco Conde, PhD, Jorge Moscat, PhD

Simultaneous Loss of Both Atypical Protein Kinase C Genes in the Intestinal Epithelium Drives Serrated Intestinal Cancer by Impairing Immunosurveillance

Immunity. 2018 Dec 18;49(6):1132-1147.e7.

Nakanishi Y, Duran A, L'Hermitte A, Shelton PM, Nakanishi N, Reina-Campos M, Huang J, Soldevila F, Baaten BJG, Tauriello DVF, Castilla EA, Bhangoo MS, Bao F, Sigal D, Diaz-Meco MT, Moscat J.

PMID: 30552022; PMCID: PMC6301096

Massimo Loda, MD

Transcriptome Deconvolution of Heterogeneous Tumor Samples with Immune Infiltration

iScience. 2018 Nov 30;9:451-460.

Wang Z, Cao S, Morris JS, Ahn J, Liu R, Tyekucheva S, Gao F, Li B, Lu W, Tang X, Wistuba II, Bowden M, Mucci L, Loda M, Parmigiani G, Holmes CC, Wang W.

PMID: 30469014; PMCID: PMC6249353

Maria Teresa Diaz-Meco Conde, PhD

ZZ-dependent regulation of p62/SQSTM1 in autophagy

Nat Commun. 2018 Oct 22;9(1):4373.

Zhang Y, Mun SR, Linares JF, Ahn J, Towers CG, Ji CH, Fitzwalter BE, Holden MR, Mi W, Shi X, Moscat J, Thorburn A, Diaz-Meco MT, Kwon YT, Kutateladze TG.

PMID: 30349045; PMCID: PMC6197226.